Coffee has anti-inflammatory and hepatoprotective properties. In the general population, drinking ≥3 cups of coffee/day has been associated with a 14% reduction in the risk of all-cause mortality. The aim of this study was to investigate the relationship between coffee consumption and the risk of allcause mortality in patients co-infected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV). Methods: ANRS CO13 HEPAVIH is an ongoing Fre